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Sarcopenia and the Worker – Is This the Next Epidemic Waiting to Happen?

Sarcopenia is defined as low muscle mass with loss of muscle strength and is often referred to as a muscle disease. (1, 4, 6) The loss of muscle strength is also referred to as dynapenia. (10)  Muscle mass and muscle strength are not synonymous.  The term sarcopenia is relatively new.  It was first coined in 1988 by Dr.  Irwin Rosenberg. (4, 5, 28, 29)

Is a sarcopenic worker costing the company more money than a non-sarcopenic worker?  What percentage of the work force might be sarcopenic?  Can this latest health disorder be reversed?

 

Although it is difficult to pinpoint the exact cost of sarcopenia, the research shows that sarcopenia in 2000 cost the United States $18.5 billion. (16)  MacEwan’s research shows the U.S. will spend up to $800 billion on sarcopenic people between 2010 and 2040 or on average $27 billion a year unless programs are put in place to reduce the risk of sarcopenia.  It is expected the cost will be even greater than $27 billion a year over the next 10 -15 years.  The cost for a hospitalized sarcopenic patient could vary from 18% up to 75% more than for a non-sarcopenic patient. (2, 11, 19)

The World Health Organization (WHO) and the CDC predict by the year 2050 there will be nearly 2 billion people worldwide over the age of 60 of which 25% or 500 million will be sarcopenic! (10, 20)  The percentage of sarcopenic people varies between 10% and 33% and sarcopenia is becoming more common after the age of 60. (19) The percent variance is mostly due to the lack of standardization on how sarcopenia is determined.  It was just recently in August 2023 that the U.S. Department of Health and Human Services launched an awareness campaign on sarcopenia.  (26)  The United States is far behind the European and Asian countries on standardizing an assessment tool for sarcopenia. (27) 

Currently, assessing for sarcopenia is timely and costly.  One of the most accurate and costly methods is using DEXA (dual-energy-X-ray-absorptiometry scan).  Other less expensive and easier to use methods and predictable models are coming to market and currently being validated.  For example, through predictive models, researchers are studying hand grip strength, calf leg circumference, gait speed, sit-to-stand and BIA (Bioelectric Impedance Assessment) or a combination of these as possible models.  The idea is to validate a model to screen people with less expense and in less time first and if the person appears to be sarcopenic then they can be screened by more accurate but costlier assessments. (1, 14, 15)

Why the concern about sarcopenia and dynapenia? 

  1. Muscle health is related to the prevention and/or management of many lifestyle disorders and chronic illnesses such as Type 2 diabetes, hypertension, cardiovascular diseases, certain cancers, joint and bone health (as well as fracture risk) and mental health such as cognition, dementia, anxiety and depression. (4, 5, 12, 21, 22, 29)  The sarcopenic person has a greater frequency and costs associated with these disorders compared to a non-sarcopenic person.
  2. Sarcopenia is one factor associated with an increased fall risk and musculoskeletal injuries. (3, 6, 20, 21, 25)
    1. With the increase in the number of workers today over the age of 60 years and that number continues to increase, sarcopenic workers will lead to increases in workers’ comp and healthcare costs.
    2. In addition, I have presented Data-Fit (IPCS) strength data showing that the industrial worker losing about 0.6 percent of their strength each year since 2014 across all age groups (20-70 years by decades), which increases the risk of the worker for sarcopenia. (8)
  3. Sarcopenia has a negative impact on activities of daily living (ADL) – getting out a of chair, climbing stairs, carrying in a bag of groceries and so on. (6, 28)
  4. Sarcopenia is also found in individuals as young as 40 years who have certain chronic diseases such as obesity, cancer, kidney dysfunction, liver disease and metabolic disorders. (28, 29)

The health and strength of muscle can be fixed – even if you are 90 years of age.  By why wait until your 90?  Resistance exercises (strength training) has been recommended by a number of health agencies including the American College of Sports Medicine for the last 15 years.

  • It is recommended resistance exercise should be done 2 -3 times per week for 60 minutes each session to help prevent sarcopenia.
  • Muscle is made to work and it must be stimulated through a great enough resistance to stay strong.

This becomes a serious concern as we age since the body naturally starts losing muscle at about age 30.  During our 40’s and 50’s, it is estimated we lose about 10-15% of our strength/muscle and then it goes downhill fast after 60 with up to a 25% loss. (1, 4, 6, 28)

 

But we should NOT accept this loss of muscle as part of aging because most of this can be prevented or delayed through resistance exercises!

 

Resistance exercise keeps the body strong and muscle healthy no matter what your age.  Before beginning any strength training, clear all activities first with your physician and start with a certified personal trainer.

Diet is critical too.  As we age, our bodies have greater difficulty processing protein.  This also contributes to muscle and strength loss.  After the age of 60, a protein supplement is recommended in addition to the daily protein intake. (21, 22)  The daily recommended protein intake after the age of 60 is about 1 gr per kilogram body weight.  This means a 200-pound (90.9 kg) person at age 60 or greater should be consuming at least 90 grams of protein each day. (21, 22)

Vitamin and mineral supplements are suggested too such as Vitamin D, antioxidant nutrients, long-chain poly-unsaturated fatty acids and dairy products. (21, 22)

Intuitively, it is conceivable, that the percentage of sarcopenic individuals/workers in the U.S. will increase dramatically by 2050 considering people today are:

  • living longer,
  • working to older ages (over 60),
  • less physically actively compared to 30 years ago,
  • gaining fat weight,
  • losing muscle strength across all age groups, and
  • long-term effects from the COVID lockdown.

 

Will these factors increase the risk of sarcopenia being diagnosed at an earlier age such as in the fifties instead of the sixties?  Therefore, should we expect more sarcopenic workers?

 

What can be done before sarcopenia becomes an epidemic?  If it does become an epidemic, it will be long lasting.  There is no quick fix.  It will take the work and cooperation of industry, occupational health, health and safety professionals, insurance companies with incentives, schools, parents, medical groups and others to implement strengthening and nutrition programs to slow the frequency of sarcopenia in the United States.  In a recent paper I wrote about the sad state of physical fitness in our children – the workers of tomorrow – which will result in an increase in the number of sarcopenic workers! (9, 13, 23)

About fifty years ago as a tenured faculty member at the University of Michigan, I received an N.I.H. grant to study heart disease risk in first graders.    My research demonstrated that when children were taught why physical activity and good nutrition were important to their health, they chose physical activity and healthy eating – they cared about their health.   We need to value our health before it is too late and quit relying on quick fixes!  I believe people want to be healthy and I believe with time this can happen. 

References

  1. Alvarez-Bustos, A., et.al. Diagnostic and Prognostic Value of Calf Circumference for Sarcopenia in Community-Dwelling Older Adults.  The Journal of Nutrition, Health and Aging.  2024: 28; 1-8
  2. Alvarez-Bustos, A., et.al. Healthcare Costs Expenditures Associated to Frailty and Sarcopenia.  BMC Geriatrics.  2022:  22; 747-758
  3. Bruyere, O., et. al. The Health Economics Burden of Sarcopenia: A System Review. 2019: 119; 61-69
  4. Cartee, GD., et.al. Exercise Promotes Healthy Aging of Skeletal Muscle.  Cell Metabolism.    23; 1034-1047
  5. Chen, LK. Skeletal Muscle Health: A Key Determinant of Healthy Aging. Archives of Gerontology and Geriatrics.  2023: 109; 105011
  6. Evans, WJ., et. Al. Sarcopenia:  No Consensus, No Diagnostic Criteria, and No Approved Indication – How Did We Get Here.    2024:46; 183-190
  7. Faigenbaum, AD., et al. May the Force be with Youth: Foundational Strength for Lifelong Development.  Curr Sports Med Rep. 2023: 22(12); 414-422
  8. Gilliam, T., Terpeluk, P. Implications of Muscular Health for Workforce Performance and Safety.  AOHC, Orlando, FL 2024
  9. Gilliam, T., The Quality of the Future Workers of America – Not Looking Good! AOHP Journal, 2024: 2; 18
  10. Gokce, E. et.al. The Mediating Role of Lower Body Muscle Strength and IGF-1 Level in the Relationship Between Age and Cognition.  A MIDUS Substudy.  Experimental Gerontology.  2024: 189; 1-7
  11. Janssen, I., et.al. The Healthcare Costs of Sarcopenia in the United States. of the American Geriatrics Society.  2004: doi.org/10.1111/j.1532-5414.2004.15415.52014.x
  12. Ju, RH., et.al. The Role of Dynapenia and Obesity on Cognitive Function in Older Adults. Clinical Nutrition ESPEN. 2024: 63; 191-196
  13. Katzmarzyk, PT., et al. Results from the United States 2018 Report Card on Physical Activity for Children and Youth.  J Phys Act Health.  2018: 15(S2); S422-S424
  14. Kim, YM., et, al. Association Between Relative Hand-grip Strength and Chronic Cardiometabolic and Musculoskeletal Disease in Koreans: A Cross-sectional Study.  Archives of Gerontology and Geriatrics.  2021: 92; 1-7
  15. Liu, S., et al. A Meta-Analysis on the Impact of Resistance Training on Phase Angle in Middle-Aged and Older Individuals.  Archives of Gerontology and Geriatrics. 2024: 119; 105318
  16. MacEwan, JP, et.al. Measuring Sarcopenia Severity in Older Adults and the Value of Effective Interventions. The Journal of Nutrition, Health and Aging.  2018: 22(10); 1253-1258
  17. Momma, H., et.al. Muscle Strengthening Activities are Associated With Lower Risk and Mortality in Major Non-Communicable Diseases: A Systematic Review and Meta-analysis of Cohort Studies.  J. Sports Med.  2022: 0:1-10.doi:10.1136/bjsports-2021-105061
  18. Myer, GD., et al. Sixty Minutes of What? A Developing Brain Perspective for Activating Children with an Integrative Exercise Approach.  Br J Sports Med. 2015: 49(23); 1510-1516
  19. Norman, K. et.al. Financial Impact of Sarcopenia or Low Muscle Mass – A Short Review.  Clinical Nutrition.  2019: 38; 1489-1495
  20. Pan, Y., et.al. Associations Between Low Muscle Mass and Clinical Characteristics of Health Population in China. Osteoporosis and Sarcopenia. 2024: 10; 35-39
  21. Prado, C.M., et.al. Advances in Muscle Health and Nutrition:  A Toolkit for Healthcare Professionals.  Clinical Nutrition.  2022: 41; 2244-2263
  22. Robinson, SM. et.al. Does Nutrition Play a Role in the Prevention and Management of Sarcopenia?  Clinical Nutrition.  2018: 37; 1121-1132.
  23. Ruas, CV., et al. Resistance Training Effects on Pubertal Children With a Risk of Developing Pediatric Dynapenia.  European Journal of Applied Physiology.  2024: 124; 2123-2137
  24. Shailendra, P., et al. Resistance Training and Mortality Risk: A Systematic Review and Meta-Analysis. Am J Prev Med 2022: 63(2); 277-285
  25. Sun, R., et.al. Effective Resistance Training on Body Composition, Muscle Strength, and Biomarker in Sarcopenic Older Adults:  A Meta-Analysis of Randomized Controlled Trials.  Archives of Gerontology and Geriatrics. 2024:  https://doi.org/10.1016/j.archger.2024.105595
  26. U.S. Department of Health and Human Services. HHS Launches National Sarcopenia Awareness Campaign.  Aug 23, 2023
  27. Weng, SE., et.al. The Evolving Landscape of Sarcopenia in Asia: A Systematic Review and Mete-Analysis Following the 2019 Asian Working Group for Sarcopenia (AWGS) Diagnostic Criteria. Archives of Gerontology and Geriatrics.  2024: doi.org/10.106/j.archger.2024.105596
  28. Yin, L., et.al. Skeletal Muscle Atrophy:  From Mechanism to Treatments.       Pharmacological Research.  2021: 172; 1-11
  29. Yuan, S. et.al. Epidemiology of Sarcopenia:  Prevalence, Risk Factors, and Consequences.  Metabolism.  2023: 144; 1-9

Tom Gilliam

About the author

Thomas B Gilliam, Ph.D.

Thomas has a Ph.D. in exercise/muscle physiology.  He has worked with isokinetic testing for 50 years in sports medicine and in Industry.  Tom is the author of Move it. Lose it. Live Healthy.  He has presented at numerous professional conferences and symposiums.  Tom has also published in scholarly journals.